%0 Journal Article %T The Relationship between Retinopathy in Diabetes Mellitus Type 2 and Severity and Extent of Myocardial Ischemia in Myocardial Perfusion Imaging %J Iranian Heart Journal %I Iranian Heart Association %Z %A Malek, Hadi %A Hedayati, Raheleh %A Yaghoobi, Nahid %A Behnia, Mahdi %A Rastgou, Fereydoon %A Bitarafan Rajabi, Ahmad %A Amouzadeh, Hedieh %A Hosseini, Shirin %A Firoozabadi, Hassan %D 2022 %\ 10/01/2022 %V 14 %N 4 %P 6-14 %! The Relationship between Retinopathy in Diabetes Mellitus Type 2 and Severity and Extent of Myocardial Ischemia in Myocardial Perfusion Imaging %K Diabetes Mellitus %K Diabetic retinopathy %K Ischemic heart disease %K Myocardial perfusion imaging %R %X Objectives: Diabetes mellitus type 2 (DM2) is one of the leading causes of morbidity andmortality owing to its role in the development of cardiovascular disease. This study sought toevaluate the relationship between diabetic retinopathy (DR) and myocardial ischemia usingmyocardial perfusion imaging (MPI).Materials and Methods: Thirty-three patients with DM2 (age =59 ± 8 years) were examined forevidence of DR. The subjects were divided into two groups on the basis of the presence [DR(+)]or absence [DR(-)] of diabetic retinopathy. MPI was performed for all the patients as well.Results: Eighteen and fifteen patients were categorized as DR(+) and DR(-), respectively.Ischemia was significantly more frequent in the DR(+) group than in the DR(-) group (p <0.05).There was also a positive association between the grade of retinopathy and the grade of ischemia(odds ratio (OR)[confidence interval (CI)95%] =7.1 [1.7-29.6], p =0.007). Severenonproliferative/proliferative DR was independently related to the summed difference andsummed stress scores (β=13.2, p =0.024 and β=15.4, p =0.013, respectively).Conclusion: The results of our study suggest that the presence of DR increases the risk ofabnormal perfusion and the degree of retinopathy is correlated with the extent and severity ofischemia in patients with DM2. (Iranian Heart Journal 2013; 13(4):6-14 ). %U http://journal.iha.org.ir/article_161816_d5fd598a313cebc1bc8d84d1f2c512c3.pdf