%0 Journal Article %T ASSESSMENT OF LEFT VENTRICULAR SYSTOLIC FUNCTION USING PULSED-WAVE SYSTOLIC MITRAL ANNULAR VELOCITIES (SM): THE PRELIMINARY RESULTS - SIMPLE AND RELEVANT %J Iranian Heart Journal %I Iranian Heart Association %Z %A DADGAR, A.A %A HAMEDANCHI, A. %A BARAK POUR, H. %A ARGHAMI, A. %D 2007 %\ 09/01/2007 %V 8 %N 3 %P 27-31 %! ASSESSMENT OF LEFT VENTRICULAR SYSTOLIC FUNCTION USING PULSED-WAVE SYSTOLIC MITRAL ANNULAR VELOCITIES (SM): THE PRELIMINARY RESULTS - SIMPLE AND RELEVANT %K LEFT VENTRICULAR SYSTOLIC FUNCTION %K TISSUE DOPPLER IMAGING %R %X Background-.Echocardiography has evolved as a well-established part of the evaluation of global myocardial function. Tissue Doppler echocardiography is a novel technique with wide applications, including estimation of myocardial systolic function. We hypothesized that velocity time integral (VTI) of systolic mitral annular velocity had a better correlation with systolic function in comparison to peak velocity. Consequently, for the first part of our investigation, we selected a population with near normal systolic function to show initially the linear correlation and secondly to obtain the normal values.Methods- We conducted a cross-sectional study at the echo lab with prospective simple nonrandom data collection on 50 consecutive patients (26 % normal, 38% CAD, 20% HTN, 10% MVP and 6% miscellaneous), mean age 45.6 yrs. (range: 18-80 yrs.) and 42% female. The exclusion criteria were prosthetic valves, LV systolic dysfunction, and/or severe regional wall motion abnormality, significant regurgitation (MR and/or AR), severe mitral annular calcification (MAC), non-sinus rhythm, paradoxical septal motion and poor endocardial line definition. All underwent complete echocardiographic study including TDI; some of the indexes of PW-TDI, with special attention to the systolic velocity of mitral annulus (Sm), were correlated with three different methods of EF measurement. Results- The mean ejection fraction and VTI of Sm were 61.68% and 1.6594, respectively. Of TDI indices, linear regression analysis showed that VTI of Sm had the strongest statistical correlation with EF measured by Simpson’s method (p=0.014, EF= 50.1 + 6.96 X VTI). Conclusion- Despite some inevitable limitations, our preliminary data suggest that peak velocity and particularly VTI of Sm in PW-TDI can be considered as reliable, rapid and reproducible indicators of preserved LV systolic function. However, we are currently conducting another complementary study to compare PW-TDI of Sm in patients with LV systolic dysfunction with or without mitral regurgitation. %U http://journal.iha.org.ir/article_83961_66ebbbdd26c7ad9d9a99edad5f8013bb.pdf