Iranian Heart Journal

Iranian Heart Journal

Comparison of Transcatheter Atrial Septal Defect Closure Between Children Weighing Less Than 15 kg and Children Weighing 15 to 20 kg

Document Type : Original Article

Authors
Osman Baspinar 1
Mehmet Kervancioglu 1
Metin Kılınc 1
Derya Aydın Sahin 1
Khaleel Al-Suwayfe 1
Arif Selcuk 2
Mehmet Adnan Celkan 2
Gokhan Gokaslan 2
1 Department of Pediatric Cardiology, Gaziantep University Medical Faculty, Gaziantep, Turkey.
2 Department of Cardiothoracic Surgery, Gaziantep University Medical Faculty, Gaziantep, Turkey.
Abstract
Background:We investigated the safety, efficacy, and follow-up results of the transcatheter closure of secundum atrial septal defects (ASDs) in children weighing less than 15 kg compared with children weighing between 15 and 20 kg.
 
Methods:During the study, 274 children weighing less than 20 kg underwent transcatheter closure. The patients were divided into 2 groups: Group I comprised 146 patients (53.3%) weighing 15 kg or less and Group II consisted of 128 patients (46.7%) weighing between 15 and 20 kg. Data were analyzed retrospectively.
 
Results:The mean age and weight of the children were 4.3 ± 1.3 years and 15.2 ± 2.4 kg. Totally, 269 interventional operations (98.2%) were considered successful. Major complications occurred in 7 patients (2.5%). The stretched ASD diameter was 14.7 ± 3.9 (7–29) mm in Group I and 15.9 ± 4.7 (7.8–28) in Group II (P =0.063). The defect diameter/body weight was 0.9 ± 0.2 (0.4–1.8) in Group I and 0.8 ± 0.2 (0.4–1.5) in Group II (P =0.001). The Amplatzer-like device diameter was 16.0 ± 4.1 (9–30) mm in Group I and 17.7 ± 5.0 (9–34) mm in Group II (P =0.004). The patch-like device diameter was 28.8 ± 4.6 (20–35) mm in Group I and 29.4 ± 4.1 (20–33) in Group II (P =0.716). The size of the delivery sheath was 8.4 ± 1.4 (6–12) F in Group I and 8.8 ± 1.5 (6–12) F in Group II (P =0.039). There were no statistically significant differences in the rates of unsuccessful procedures and complications between the patient groups (P =0.762 and P =0.836, correspondingly).
 
Conclusions: The transcatheter closure of secundum ASDs in small children is feasible and is not associated with a greater risk of significant complications. (Iranian Heart Journal 2021; 22(3): 33-43)
Keywords
Transcatheter closure
Atrial septal defects
Small children
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Iranian Heart Journal
Volume 22, Issue 3
Summer 2021
Pages 33-43