Membranous Interventricular Septal Aneurysm: A Case Report

Document Type : Case Report


1 Department of Cardiovascular Surgery, Imam Hossein Medical Center, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran.

2 Heart Valve Disease Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IR Iran.


Aneurysmal formation in the membranous part of the interventricular septum is a very rare heart defect. The interventricular membranous septal (IVMS) aneurysm is mainly found in conjunction with ventricular septal defects or other congenital cardiac anomalies. It has often been found as an asymptomatic phenomenon, so that it is diagnosed incidentally during imaging evaluations of heart structures. Thereby, its presence without other congenital cardiac anomalies is a very uncommon entity. Herein, we describe a 77-year-old man with the chief complaints of chest pain and dyspnea on exertion. The physical examination was normal except for the presence of ejection-type systolic murmurs along the left sternal border in the aortic area on auscultation. The patient’s preoperative transthoracic echocardiography revealed severe aortic valve stenosis, and his transesophageal echocardiography during aortic valve replacement revealed an incidental IVMS aneurysm. The aneurysm was resected concomitantly with aortic valve replacement surgery, and he was asymptomatic and stable in the follow-up period. (Iranian Heart Journal 2021; 22(3): 115-118)


  1. Carcano C, Kanne JP, Kirsch J. Interventricular membranous septal aneurysm: CT and MR manifestations. Insights Imaging 2016;7:111-117.
  2. Karagöz A, Çelik A, Vural A, Başer B. An incidentally detected giant membranous interventricular septal aneurysm secondary to previous surgery for subaortic valvular stenosis BMJ Case Rep, 2014.
  3. Naidu A, Ricketts M, Goela A, Shoemaker G, Li S. Incidental discovery of a membranous ventricular septal aneurysm in two dissimilar patients. Case Rep Cardiol 2012;2012:324326.
  4. Yavuz S, Eris C, Goncu T, Sezen M, Ata Y, Turk T. An incidental aneurysm of the interventricular membranous septum. Arch Iran Med 2010;13:363-364.
  5. Afaneh AB, Wymer DC, Kraft S, Winchester DE. Membranous ventricular septal aneurysm diagnosed by means of cardiac computed tomography. Tex Heart Inst J 2012;39:450-451.
  6. Yilmaz AT, Ozal E, Arslan M, Tatar H, Oztürk OY. Aneurysm of the membranous septum in adult patients with perimembranous ventricular septal defect. Eur J Cardiothorac Surg 1997;11:307-311.
  7. Fabijanic D, Bulat C, Batinic T, Carevic V, Caljkusic K. Membranous Ventricular Septum Aneurysm as a Cause of Recurrent Transient Ischemic Attack. J Cardiovasc Ultrasound 2012;20:114-115.
  8. Sharma A, Kern MJ, Callicoat P, Aguirre F, Labovitz A, Willman VL. Severe subpulmonic outflow obstruction caused by aneurysm of the membranous ventricular septum: Diagnosis by transesophageal echocardiography. American Heart Journal 1992;123:810-814.
  9. Canale JM, Sahn DJ, Valdes-Cruz LM, Allen HD, Goldberg SJ, Ovitt TW. Accuracy of two-dimensional echocardiography in the detection of aneurysms of the ventricular septum. American Heart Journal 1981;101:255-259.
  10. EDELSTEIN J, CHARMS BL. Ventricular Septal Aneurysms. Circulation 1965;32:981-984.