Document Type : Original Article
Department of Cardiology and Vascular Medicine, Faculty of Medicine, Hasanuddin University, Integrated Heart Centre, Wahidin Sudirohusodo General Hospital, Makassar, South Sulawesi, Indonesia.
Faculty of Medicine, Hasanuddin University, Makassar, South Sulawesi, Indonesia.
Background: The management of low-burden premature ventricular complexes (PVCs) (<10%) is currently a matter of debate among clinicians. Several small studies have shown an increased risk for left ventricular dysfunction in a lower PVC burden. Radiofrequency ablation is known to have favorable effects on PVC frequencies and left ventricular dysfunction. However, data are scarce regarding ablation in patients with low-burden PVCs, especially its benefits on symptom burden and the quality of life. This study aimed to compare symptom burden and the quality of life before and 6 months after ablation.
Methods: Thirty-one patients with low-burden PVCs who underwent radiofrequency ablation were assessed. The ASTA (Arrhythmia-Specific questionnaire in Tachycardia and Arrhythmia) was used to assess symptom burden and the quality of life in the patients. The score was calculated before and 6 months after ablation.
Results: Significant differences existed in the mean scores before and 6 months after ablation concerning the ASTA burden scale symptom score (38.83 vs 4.45; P<0.05), the ASTA health-related quality of life (HRQoL) physical subscale (30.30 vs 1.91; P<0.05), the ASTA HRQoL mental subscale (32.41 vs 4.51; P<0.05), and the ASTA HRQoL total scale (32.09 vs 2.90; P<0.05).
Conclusions: Radiofrequency ablation was associated with a favorable outcome in terms of symptom burden and the quality of life in our patients with low-burden PVCs in the short term. (Iranian Heart Journal 2021; 22(4): 25-33)