Comparison of the Mitral Regurgitation Volume Derived From Transthoracic Echocardiography Between the HeartModel and Continuity Equation Methods in Patients With Severe Mitral Regurgitation

Document Type : Original Article


1 Heart Valve Disease Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IR Iran.

2 Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IR Iran.


Background: We compared the mitral regurgitation (MR) volume measured between 2 methods: the 2D continuity equation transthoracic echocardiography (2D CE-TTE) and the 3D HeartModel transthoracic echocardiography (3D HM-TTE).
Methods: Thirty-five patients at a mean age of 53.31 years (SD=15.16) were enrolled. All the patients were diagnosed with severe MR via transesophageal echocardiography. For the comparison of the MR volumes yielded by the 2 methods, the Bland–Altman chart and linear regression analyses were conducted.
Results: The Bland–Altman analysis showed a mean difference of −89.30 mL between the MR volume measurements of the 2 methods, and the linear regression resulted in a standardized coefficient β of −0.831 (P<0.001). Hence, the analysis showed a significant proportional bias between 2D CE-TTE and 3D HM-TTE.
Conclusions: Overall, we observed that 2D CE-TTE overestimated the MR volume measured by 3D HM-TTE by about 30%. (Iranian Heart Journal 2023; 24(1): 62-68)


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