Document Type : Original Article
Cardiac Electrophysiology Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences Tehran, IR Iran.
Department of Cardiac Electrophysiology, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, IR Iran.
Rajaie Cardiovascular Medical and Research Center, School of Medicine, Iran University of Medical Sciences, Tehran, IR Iran.
Cardiovascular Intervention Research Center, Rajaie Cardiovascular, Medical and Research Center, Iran University of Medical Sciences, Tehran, IR Iran.
Background: Atrioventricular nodal reentry tachycardia (AVNRT) is the most common type of supraventricular tachycardia, and catheter slow pathway ablation is the first-line therapy in this arrhythmia. The endpoint for the successful ablation of AVNRT is the noninducibility of the tachycardia rather than the complete ablation or modification/ablation of slow pathways. We aimed to compare heart rate variability (HRV) parameters between slow pathway complete ablation and slow pathway modification/ablation for AVNRT.
Methods: The current study enrolled 78 eligible patients with AVNRT. Slow pathway complete ablation was performed on 49 patients, and 29 patients underwent slow pathway modification/ablation. HRV parameters on 24-hour Holter monitoring were compared before and 30 days after ablation between these 2 groups.
Results: HRV parameters, consisting of the mean heart rate, the standard deviation of normal-to-normal RR intervals over 24 hours (SDNN), the standard deviation of the average NN intervals for all 5-minute intervals in a 24-hour continuous electrocardiographic recording (SDANN), and a percent NN interval exceeding 50 milliseconds from the prior interval (PNN50), were not significantly different in the group with complete slow pathway ablation. The comparison between pre and post-intervention entities revealed statistically significant differences in SDNN (P=0.041) and PNN50 (P=0.008) in the group with slow pathway modification/ablation. Additionally, PNN50 was significantly lower in the modification/ablation group than in the complete ablation group.
Conclusions: We noted negligible differences regarding HRV-associated indices between the slow pathway complete ablation and modification/ablation for AVNRT groups. (Iranian Heart Journal 2023; 24(2): 62-68)