Relationship Between the Serum Levels of Nonfasting Triglyceride and the Severity of Coronary Artery Disease


1 Ahvaz Atherosclerosis Research Center , Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran

2 Atherosclerosis Research Center, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, IR Iran


Background: Cardiovascular diseases are a major cause of death in both men and women around the
world. Studies have shown that hypertriglyceridemia is an important risk factor for such
diseases. While triglyceride levels after a meal increase, the relationship between postprandial
triglyceride levels and the severity of coronary artery disease is still unproven.
This study aimed to determine the plasma levels of triglyceride after a meal in patients with
different types of coronary heart disease.
Method: In this epidemiological study, 416 patients from among those referred to Golestan Hospital in
Ahvaz were selected based on the results of angiography and were classified to type 1 to 4
groups comprising 69, 99, 83, and 165 individuals respectively, and their age and sex were
recorded. From all the individuals, a blood sample was taken 2 hours after a meal. The data
were analyzed using the Tukey test.
Results: The mean age of the patients was 58.4 years. There was only a significant difference between
the patients with type 1 (normal patients) and those with type 4 (with severe coronary artery
disease) (142 ± 67.1 mg/dL vs 188 ± 99.3 mg/dL; P < 0.001). Furthermore, no significant
difference in the mean triglyceride level was observed in both sexes between the different types
(P > 0.05).
Conclusions: The results showed that the mean triglyceride serum level after a meal in our patients
with severe coronary artery disease (type 4) was higher than that in the other groups.
Hypertriglyceridemia after a meal may be a major factor in coronary heart disease.