Assistant professor of cardiology Hamedan University
Assistant professor of endocrinology Hamedan University
The aim of this study was to determine thyrotoxicosis frequency in patients with heart failure hospitalized in Ekbatan Cardiac Hospital, Hamadan.
Material & Methods: In this cross-sectional, descriptive study, patients with heart failure hospitalized in a cardiac hospital were characterized on the basis of physical examination (the Framingham criteria) and evaluation of hospital records. The patients were thereafter assessed for the presence of thyroid dysfunction. For all the patients, T3, T4, and TSH tests were done via the ELISA method. For every patient, a questionnaire was completed, including the results of the tests and also data on age, sex, duration of cardiac disease, and medical history.
Results: From 200 patients in this study, 90 (45%) patients were male and 110 (55%) were female.
From these patients, 3 (1.5%) had thyrotoxicosis, 2 (1%) had hypothyroidism, 13 (6.5%) had sub-clinical hyperthyroidism, 12 (60%) had sub-clinical hypothyroidism, and 170 (85%) had no thyroid dysfunction. The mean time of heart failure (history of cardiac disease) in the patients with thyrotoxicosis was 4±1 years and in the other patients (without thyrotoxicosis) was 5.43±2.4 years. The mean age in the patients with thyrotoxicosis was 73.33±5.77 years and in the other patients was 63.98±11.86 years. Five patients with heart failure used Amiodarone and none of them had thyroid dysfunction.
Conclusion: This evaluation showed that the frequency of thyrotoxicosis in our patients with heart failure was of low prevalence. Also, the frequency of thyrotoxicosis was not associated with sex, age, and duration of cardiac disease.