Background- Prognosis determination after acute myocardial infarction (AMI) is an important issue; the purpose of the study was to evaluate the relation between 24-hour ambulatory electrocardiography (24hr ECG) databases with 6-month cardiac events in post-MI patients with low ejection fraction.
Methods- A cohort study was performed on 100 consecutive patients (62 men, 38 women) with AMI and mean ejection fraction 34.94±5.23%. These patients had 24-hr ECG monitoring and recordings were reviewed for ST-segment depression, complex premature ventricular contractions (PVC), frequent PVCs and heart rate variability. Then patients were followed for at least 6 months for readmission for cardiac causes, repeat MI, sudden cardiac death (SCD) and non-sudden cardiac death. The data were analyzed by multiple logistic regressions.
Results- There were significant positive relationships between: 1) complex PVCs (P<0.002) and ST depression (p<0.002) with readmission, 2) ST depression with repeat MI (p<0.002), 3) reduced heart rate variability (HRV) with sudden cardiac death (p<0.001), and 4) complex PVCs with non-sudden cardiac death (p<0.036).
Conclusion- It seems that 24hr ECG may be a useful method for more risk stratification of high risk patients (Iranian Heart Journal 2003; 4 (2, 3):50-54).