Cardiovascular Research Center, Nemazi Hospital, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
Background- Coronary artery diseases are the leading cause of death in the developing countries, including Iran. Continued advances in medical and surgical techniques, combined with effective and focused programs in cardiac rehabilitation, are critical to reduce the overall incidence of coronary artery diseases. Now it is recommended that all survivors of acute myocardial infarction receive antiplatelet drugs, beta-adrenergic blocking agents, ACE inhibitors and statins. However, studies show that the ratio of prescribing these drugs is far lower than ideal. This study has been designed to evaluate these ratios in Iran.
Methods- In a descriptive, cross-sectional retrograde study, the ratio of prescribing the above-mentioned drugs in 912 randomly selected patients from Shiraz University hospitals who met WHO criteria for myocardial infarction from March 2000 to March 2001 were studied. Trained medical students recorded demographical data, location of infarction, risk factors and pharmacologic therapy at the time of the discharge of the patients from the medical recording files in a standardized questionnaire.
Results- The mean age of the studied patients was 61±12 years. The most frequently prescribed drugs were antiplatelet agents and the least frequent ones were statins. There were statistically significant relationships between cigarette smoking and beta-adrenergic blocking agents administration, hyperlipidemia and statins administration and hypertension and ACE inhibitors administration.
Conclusion- There is a need for improvement in secondary prevention in patients with myocardial infarction at the time of hospital discharge, and risk factor evaluation and suitable drug therapy is necessary for secondary prevention in Shiraz University hospitals (Iranian Heart Journal 2003; 4 (4):44-48).