Iranian Heart Journal

Iranian Heart Journal

RESULTS OF HEART VALVE HOMOGRAFT IMPLANTATION IN A MAJOR REFERRAL CENTER IN IRAN

Authors
M.Y. Aarabi
P. N. Davari
M. Meraji
a. Shahmohammadi
M. Dalir Rooyfard
M. A. Yousefnia
G.R. Omrani
M. B. Tabatabaee
A. Zavarehee
VALIASR AVE TEHRAN- IRAN
Abstract
Background- Heart Valve homografts have been used in reconstructions of right and ‎left ventricular outflow tract (RVOT and LVOT) for nearly 50 years now with ‎varying results. Methods- The outcome of homograft implantation was analyzed in ‎‎101 patients who received 108 cryopreserved homografts for the reconstruction of ‎RVOT and LVOT between April 1993 and March 2003‎‏.‏ Results- 88.2% aortic valve and 11.7% pulmonic valve homografts were used. ‎Median age at implantation was 10.0 years (Mean: 13.1 ± 10.6 years, range: 5 months ‎to 57 years). Endpoints included: (1) patient survival, (2) homograft failure (valve ‎explant or late death) and (3) homograft dysfunction (homograft insufficiency or ‎homograft stenosis). Mean follow up duration was 2.9 ± 2.4 years. There were 11 ‎homograft dysfunctions requiring reoperation with the mean longevity of 4.4 ± 2.3 ‎years. We had only one late death due to congestive heart failure (CHF), and all the ‎other deaths (23.7% of the patients) occurred perioperatively. The quality of life of ‎most of the survivors is good‏.‏ Conclusion- Early and mid-term results of homograft implantation are good, but long-‎term results remain to be investigated (Iranian Heart Journal 2003; 4 (4):6-15‎‏).
Keywords
HOMOGRAFT A CONGENITAL HEART SURGERY
Iranian Heart Journal
Volume 4, Issue 4
Spring 2003
Pages 6-16