DEPARTMENT OF CARDIOLOGY, SHAHEED RAJAIE CARDIOVASCULAR, MEDICAL AND RESEARCH CENTER, TEHAN, IRAN
Abstract
Objectives- Both high-sensitivity C-reactive protein (hs-CRP) and spiral computed tomography coronary artery calcium score are valid markers of cardiovascular risk. It is unknown whether hs-CRP is a marker of atherosclerotic burden or whether it reflects a process leading to acute coronary events. Methods- We studied the association of high-sensitivity C-reactive protein and coronary calcium score in 143 patients that were candidates for coronary artery bypass graft surgery. Results- In our cross sectional study we found no significant association between high-sensitivity C-reactive protein and coronary calcium score in bivariants (p=0.162) and multivariable (p=0.062) analysis, but in patients who did not use statins, this association was significant and positive in bivariant (p=0.001) and in multivariate analysis this association was negative and significant (p=0.008). Conclusion- High-sensitivity C-reactive protein was not associated with coronary calcium score. The relation between C-reactive protein and clinical events might not be related to atherosclerotic burden. Measures of inflammation, such as C-reactive protein, and indices of atherosclerosis, such as coronary calcium score, are likely to provide distinct information regarding cardiovascular risk.
HOSSEINSABET, A., MOHEBI, B., MOHEBI, A., & ALMASI, A. (2009). C - REACTIVE PROTEIN AND CORONARY CALCIUM SCORE ASSOCIATION IN CORONARY ARTERY DISEASE. Iranian Heart Journal, 10(1), 40-47.
MLA
A HOSSEINSABET; BAHRAM MOHEBI; AHMAD MOHEBI; A.R. ALMASI. "C - REACTIVE PROTEIN AND CORONARY CALCIUM SCORE ASSOCIATION IN CORONARY ARTERY DISEASE". Iranian Heart Journal, 10, 1, 2009, 40-47.
HARVARD
HOSSEINSABET, A., MOHEBI, B., MOHEBI, A., ALMASI, A. (2009). 'C - REACTIVE PROTEIN AND CORONARY CALCIUM SCORE ASSOCIATION IN CORONARY ARTERY DISEASE', Iranian Heart Journal, 10(1), pp. 40-47.
VANCOUVER
HOSSEINSABET, A., MOHEBI, B., MOHEBI, A., ALMASI, A. C - REACTIVE PROTEIN AND CORONARY CALCIUM SCORE ASSOCIATION IN CORONARY ARTERY DISEASE. Iranian Heart Journal, 2009; 10(1): 40-47.
)