Background -The aim of this study was to determine whether characteristics, presentation and outcome differences based on the patient's gender occur after acute myocardial infarction (AMI). Methods- By this prospective multivariate study; we assessed 500 consecutive first infarct survivors (353 men and 147 women), who were admitted to our heart center over a period of2 years. Results- On average, women were 6.2 years older than men (P=0.030). According to multivariate analysis women were less likely than men to be smokers (p=0.0001) and more likely to have underlying hypertension (P=0.02), diabetes (P=0.041), previous angina (P=0.041), non-Q-wave infarctions (P=0.019) and left ventricular ejection fraction < 40% (P=0.038). Men had significantly more 3-vessel coronary artery disease [relative risk (RR) = 1.8, 95% CI, (1.21- 2.38), P=0.02]. In-hospital mortality rate was 19% for women and 12% for men [RR =1.51, 95% CI (0.95-1.82), P=0.044); in addition, the mortality rate at I-year follow-up was 27% for women and 15% for men [RR=1.61, 95% CI (1.04-2.51), P=0.039]. However, after an age matched analysis, we found no significant differences between men and women for in-hospital mortality. Also, our I-year follow-up showed that the mortality rate in women was remarkably similar to the age-matched groups in men, but men had more CABG procedures in hospitalization and 1-year follow-up period [RR= 2.34,95% CI (1.35-3.0), P=0.033].
Conclusion- The age-matched mortality rate in this study was the same for men and women, excluding the greater frequency of 3-vessel involvement, advanced left main coronary disease and greater frequency of CABG operations in men.
HAKIM, S., ALIZADEH ASL, A., AZAR FARIN, R., & SAMADIKHAH, J. (2007). THE INFLUENCE OF GENDER ON OUTCOME IN PATIENTS WITH FIRST ACUTE MYOCARDIAL INFARCTION. Iranian Heart Journal, 8(1), 30-32.
MLA
S.H. HAKIM; A. ALIZADEH ASL; R. AZAR FARIN; J. SAMADIKHAH. "THE INFLUENCE OF GENDER ON OUTCOME IN PATIENTS WITH FIRST ACUTE MYOCARDIAL INFARCTION". Iranian Heart Journal, 8, 1, 2007, 30-32.
HARVARD
HAKIM, S., ALIZADEH ASL, A., AZAR FARIN, R., SAMADIKHAH, J. (2007). 'THE INFLUENCE OF GENDER ON OUTCOME IN PATIENTS WITH FIRST ACUTE MYOCARDIAL INFARCTION', Iranian Heart Journal, 8(1), pp. 30-32.
VANCOUVER
HAKIM, S., ALIZADEH ASL, A., AZAR FARIN, R., SAMADIKHAH, J. THE INFLUENCE OF GENDER ON OUTCOME IN PATIENTS WITH FIRST ACUTE MYOCARDIAL INFARCTION. Iranian Heart Journal, 2007; 8(1): 30-32.