CARDIOVASCULAR RESEARCH CENTER, AFSHAR HOSPITAL, JOMHOURI ESLAMI BOULEVARD, YAZD, ISLAMIC REPUBLIC OF IRAN
Background: The relationship between microalbuminuria and coronary events has been established. In the case of retinopathy; however, the issue is controversial. The aim of this study was to determine the relationship between diabetic retinopathy and myocardial infarction as a major presentation of CAD.
Methods: 180 diabetic patients with and without myocardial infarction were studied in this analytical case-control study. Each group consisted of 38 females and 52 males with a mean age (SD) of 58.27 (11.38) years in the case group and 56.85 (11.11) years in the control group. The two groups were matched except for history of myocardial infarction.
Results: SPSS analysis of the data showed no significant differences between the two groups in terms of age and duration of diabetes (DM) [10.34 (8.17) years in the case vs. 10.54 (8.22) years in control group]. There was a significant relationship between the severity of retinopathy and duration of DM (p=0.05), but no significant relation between sex and retinopathy severity was obtained (p=0.1 in case vs. p=0.3 in control group). Although no significant difference between the two groups in terms of the severity of retinopathy (p=0.5) was detected, in the subgroup of the diabetic patients with MI and less than 5 years' duration of DM, retinopathy was more common (p=0.05).
Conclusion: Premature retinopathy can predict coronary events. Immediate CAD screening of all diabetic patients with retinopathy is recommended.