SHAHEED RAJAIE CARDIOVASCULAR MEDICAL CENTER, VALI-E-ASR AVE., MELLAT PARK, TEHRAN, IRAN
Abstract
Background: Whether or not atherosclerosis is an infectious disease is not clear. In addition to the classic risk factors, a number of infectious agents such as Chlamydiapneumoniae have been implicated as a possible cause of atherosclerosis. The aim of this study was to determine the presence of C. pneumoniae DNA in atherosclerotic plaques by PCR. Method: Thirty patients (mean age 59±8; 18 male, 12 female) undergoing coronary bypass grafting were included in the study. Results: C. pneumoniae DNA was found in 16 (53%) out of the 30 specimens having been dissected from the subjects' coronary arteries. The presence of C. pneumoniae DNA in a considerable number of these plaques supports the notion that it may have a role in the development of atherosclerosis. Conclusion: The results of studies seeking to clarify the nature of the link between infection and coronary heart disease are eagerly awaited.
MOMTAHEN, M., GHAFARNEZHAD, M., TABARESTANI, S., ALMASI, N., SAMIEI, S. (2005). DETECTION OF CHLAMYDIA PNEUMONIA DNA IN CORONARY ATHEROSCLEROTIC PLAQUES BY PCR. Iranian Heart Journal, 6(4), 49-54.
MLA
M. MOMTAHEN; M. GHAFARNEZHAD; S. TABARESTANI; N. ALMASI; S. SAMIEI. "DETECTION OF CHLAMYDIA PNEUMONIA DNA IN CORONARY ATHEROSCLEROTIC PLAQUES BY PCR". Iranian Heart Journal, 6, 4, 2005, 49-54.
HARVARD
MOMTAHEN, M., GHAFARNEZHAD, M., TABARESTANI, S., ALMASI, N., SAMIEI, S. (2005). 'DETECTION OF CHLAMYDIA PNEUMONIA DNA IN CORONARY ATHEROSCLEROTIC PLAQUES BY PCR', Iranian Heart Journal, 6(4), pp. 49-54.
VANCOUVER
MOMTAHEN, M., GHAFARNEZHAD, M., TABARESTANI, S., ALMASI, N., SAMIEI, S. DETECTION OF CHLAMYDIA PNEUMONIA DNA IN CORONARY ATHEROSCLEROTIC PLAQUES BY PCR. Iranian Heart Journal, 2005; 6(4): 49-54.
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