SHAHEED RAJAIE CARDIOVASCULAR MEDICAL CENTER, VALI-E-ASR AVE., MELLAT PARK, TEHRAN, IRAN
Abstract
Background: Whether or not atherosclerosis is an infectious disease is not clear. In addition to the classic risk factors, a number of infectious agents such as Chlamydiapneumoniae have been implicated as a possible cause of atherosclerosis. The aim of this study was to determine the presence of C. pneumoniae DNA in atherosclerotic plaques by PCR. Method: Thirty patients (mean age 59±8; 18 male, 12 female) undergoing coronary bypass grafting were included in the study. Results: C. pneumoniae DNA was found in 16 (53%) out of the 30 specimens having been dissected from the subjects' coronary arteries. The presence of C. pneumoniae DNA in a considerable number of these plaques supports the notion that it may have a role in the development of atherosclerosis. Conclusion: The results of studies seeking to clarify the nature of the link between infection and coronary heart disease are eagerly awaited.
MOMTAHEN, M., GHAFARNEZHAD, M., TABARESTANI, S., ALMASI, N., & SAMIEI, S. (2005). DETECTION OF CHLAMYDIA PNEUMONIA DNA IN CORONARY ATHEROSCLEROTIC PLAQUES BY PCR. Iranian Heart Journal, 6(4), 49-54.
MLA
M. MOMTAHEN; M. GHAFARNEZHAD; S. TABARESTANI; N. ALMASI; S. SAMIEI. "DETECTION OF CHLAMYDIA PNEUMONIA DNA IN CORONARY ATHEROSCLEROTIC PLAQUES BY PCR". Iranian Heart Journal, 6, 4, 2005, 49-54.
HARVARD
MOMTAHEN, M., GHAFARNEZHAD, M., TABARESTANI, S., ALMASI, N., SAMIEI, S. (2005). 'DETECTION OF CHLAMYDIA PNEUMONIA DNA IN CORONARY ATHEROSCLEROTIC PLAQUES BY PCR', Iranian Heart Journal, 6(4), pp. 49-54.
VANCOUVER
MOMTAHEN, M., GHAFARNEZHAD, M., TABARESTANI, S., ALMASI, N., SAMIEI, S. DETECTION OF CHLAMYDIA PNEUMONIA DNA IN CORONARY ATHEROSCLEROTIC PLAQUES BY PCR. Iranian Heart Journal, 2005; 6(4): 49-54.
)