Prevalence of Hepatitis C Virus Infection Among Patients With Cardiovascular Disorders in a University Hospital in Iran March 2015 to September 2016

Authors

Rajaie Cardiovascular, Medical, and Research Center, Iran University of Medical Sciences, Tehran, IR Iran

Abstract

Background: Hepatitis C virus (HCV) infection is prevalent and potentially fatal in patients with cirrhosis and hepatocellular carcinoma. The main routes of transmission are via sharing syringes, blood products, and sexual contact. We sought to determine the incidence of HCV infection among patients with cardiovascular diseases (CVDs) in an 18-month period. Methods: During a period of 18 months, 39450 patients with CVDs underwent HCV Ab measurement via the ELISA technique. Hbs Ag was also checked among HCV-positive cases in Rajaie Cardiovascular, Medical, and Research Center in Tehran, Iran 2015 to 2016. Results: The patients were aged between 4 months and 97 years. In 72 out of the 39450 patients (0.18%), HCV Ab was positive and 2 out of the 72 patients (2.7%) were also positive for HBs Ag. Conclusions: The prevalence of HCV infection in patients affected by CVDs in a single referral center in Iran may be lower than that in other groups.

Keywords


  1. Alter-Miriam, J., Epidemiology of hepatitis C in the West. Semin Liver Dis, 1995. 15: p. 5-14.
  2. Sarbah, S.A. and Z.M. Younossi, Hepatitis C: an update on the silent epidemic. Journal of clinical gastroenterology, 2000. 30(2): p. 125-143.
  3. Mohebbi, S.R., et al., Hepatitis C and hepatitis B virus infection: epidemiology and risk factors in a large cohort of pregnant women in Lorestan, West of Iran. Hepat Mon, 2011. 11(9): p. 736-9.
  4. Hahn, J.A., et al., Hepatitis C virus infection and needle exchange use among young injection drug users in San Francisco. Hepatology, 2001. 34(1): p. 180-187.
  5. Mitsui, T., et al., Hepatitis C virus infection in medical personnel after needlestick accident. Hepatology, 1992. 16(5): p. 1109-1114.
  6. Ohto, H., et al., Transmission of hepatitis C virus mothers to infants. New England Journal of Medicine, 1994. 330(11): p. 744-750.
  7. Wasley, A. and M.J. Alter. Epidemiology of hepatitis C: geographic differences and temporal trends. in Seminars in liver disease. 2000. Copyright© 2000 by Thieme Medical Publishers, Inc., 333 Seventh Avenue, New York, NY 10001, USA. Tel.: 1 (212) 584-4663.
  8. KARAWI, M.A.A., et al., Hepatitis C virus infection in chronic liver disease and hepatocellular carcinoma in Saudi Arabia. Journal of gastroenterology and hepatology, 1992. 7(3): p. 237-239.
  9. Bell, J., et al., Hepatitis C virus in intravenous drug users. The Medical Journal of Australia, 1990. 153(5): p. 274-276.
  10. Kolho, E., et al., Transmission of hepatitis C virus to sexual partners of seropositive patients with bleeding disorders: a rare event. Scandinavian journal of infectious diseases, 1991. 23(6): p. 667-670.
  11. Saketi, J.R., et al., Prevalence of hepatitis C virus infection among haemodialysis patients in West Java, Indonesia, in Tropical Diseases. 2003, Springer. p. 201-209.
  12. Das, S. and M. Kumar, Association of blood group types to hepatitis B and hepatitis C virus infection among blood donors: a five years institutional based study. Int J Basic Appl Med Sci, 2012. 2: p. 191-5.
  13. Ataei, B., et al., Prevalence of anti HCV infection in patients with beta-thalassemia in Isfahan-Iran. International journal of preventive medicine, 2012. 3(3S).
  14. Alavian, S.M., Hepatitis C infection in Iran; A review article. Iran J Clin Infect Dis, 2009. 4(1): p. 47-59.