SHAHEED RAJAIE CARDIOVASCULAR MEDICAL CENTER, VALI-E-ASR AVE., MELLAT PARK, TEHRAN, IRAN
Abstract
Background: Whether or not atherosclerosis is an infectious disease is not clear. In addition to the classic risk factors, a number of infectious agents such as Chlamydiapneumoniae have been implicated as a possible cause of atherosclerosis. The aim of this study was to determine the presence of C. pneumoniae DNA in atherosclerotic plaques by PCR. Method: Thirty patients (mean age 59±8; 18 male, 12 female) undergoing coronary bypass grafting were included in the study. Results: C. pneumoniae DNA was found in 16 (53%) out of the 30 specimens having been dissected from the subjects' coronary arteries. The presence of C. pneumoniae DNA in a considerable number of these plaques supports the notion that it may have a role in the development of atherosclerosis. Conclusion: The results of studies seeking to clarify the nature of the link between infection and coronary heart disease are eagerly awaited.
MOMTAHEN,M , GHAFARNEZHAD,M , TABARESTANI,S , ALMASI,N and SAMIEI,S . (2005). DETECTION OF CHLAMYDIA PNEUMONIA DNA IN CORONARY ATHEROSCLEROTIC PLAQUES BY PCR. Iranian Heart Journal, 6(4), 49-54.
MLA
MOMTAHEN,M , , GHAFARNEZHAD,M , , TABARESTANI,S , , ALMASI,N , and SAMIEI,S . "DETECTION OF CHLAMYDIA PNEUMONIA DNA IN CORONARY ATHEROSCLEROTIC PLAQUES BY PCR", Iranian Heart Journal, 6, 4, 2005, 49-54.
HARVARD
MOMTAHEN M, GHAFARNEZHAD M, TABARESTANI S, ALMASI N, SAMIEI S. (2005). 'DETECTION OF CHLAMYDIA PNEUMONIA DNA IN CORONARY ATHEROSCLEROTIC PLAQUES BY PCR', Iranian Heart Journal, 6(4), pp. 49-54.
CHICAGO
M MOMTAHEN, M GHAFARNEZHAD, S TABARESTANI, N ALMASI and S SAMIEI, "DETECTION OF CHLAMYDIA PNEUMONIA DNA IN CORONARY ATHEROSCLEROTIC PLAQUES BY PCR," Iranian Heart Journal, 6 4 (2005): 49-54,
VANCOUVER
MOMTAHEN M, GHAFARNEZHAD M, TABARESTANI S, ALMASI N, SAMIEI S. DETECTION OF CHLAMYDIA PNEUMONIA DNA IN CORONARY ATHEROSCLEROTIC PLAQUES BY PCR. Iranian Heart Journal. 2005;6(4):49-54.
