Iranian Heart Association Iranian Heart Journal 18 1 2017 03 01 Cardiovascular Magnetic Resonance in Predicting the Reduction in Pulmonary Artery Pressure in Patients With Mitral Stenosis After Surgical or Interventional Treatment 30 36 82756 EN Hamidreza Sanati Cardiovascular Intervention Research Center, Rajaie Cardiovascular , Medical , and Research Center, Iran University of Medical Sciences, Tehran, I.R. Iran Reza Rezaei Tabrizi Rajaie Cardiovascular , Medical , and Research Center, Iran University of Medical Sciences, Tehran, I.R. Iran Hamid Reza Pouraliakbar Rajaie Cardiovascular , Medical , and Research Center, Iran University of Medical Sciences, Tehran, I.R. Iran Ali Zahedmehr Cardiovascular Intervention Research Center, Rajaie Cardiovascular , Medical , and Research Center, Iran University of Medical Sciences, Tehran, I.R. Iran Ata Firouzi Cardiovascular Intervention Research Center, Rajaie Cardiovascular , Medical , and Research Center, Iran University of Medical Sciences, Tehran, I.R. Iran Farshad Shakerian Cardiovascular Intervention Research Center, Rajaie Cardiovascular , Medical , and Research Center, Iran University of Medical Sciences, Tehran, I.R. Iran Reza Kiani Cardiovascular Intervention Research Center, Rajaie Cardiovascular , Medical , and Research Center, Iran University of Medical Sciences, Tehran, I.R. Iran Nasim Naderi Rajaie Cardiovascular , Medical , and Research Center, Iran University of Medical Sciences, Tehran, I.R. Iran Journal Article 2019 02 15 Background: Pulmonary hypertension (PH) is a common consequence of mitral stenosis (MS).<br />After treatment, PH reverses depending on the chronicity and severity of MS. The<br />characteristic changes in the pulmonary artery (PA) secondary to an elevated pulmonary<br />artery pressure (PAP) can be evaluated via cardiovascular magnetic resonance imaging<br />(CMR). In this study, we aimed to evaluate if there was any correlation between PAP and<br />hemodynamic findings measured by CMR and whether these findings could be useful in<br />predicting the PAP response after MS relief.<br />Methods: Thirty-three patients with a diagnosis of severe MS, who were candidated for<br />percutaneously transvenous mitral commissurotomy (PTMC) or mitral valve replacement<br />(MVR), were included. CMR was performed in all of them before the procedure and PA<br />distensibility, PA peak velocity, PA forward volume, and PA forward flow were measured.<br />Transthoracic echocardiography was performed at baseline, immediately after the<br />procedure, and 3 months after MS relief for the assessment systolic PAP.<br />Results: Thirty-three patients with a diagnosis of MS+PH (15 PTMC and 18 MVR) were enrolled<br />in this study. The mean PAP at baseline catheterization ranged from 25 to 70 mm Hg. There<br />was a significant drop in systolic PAP immediately after the procedure and 3 months after<br />MS relief. There was no relationship between the PA distensibility index and systolic PAP<br />changes after MS relief. PA peak velocity was significantly higher in the patients with ><br />50% drops in their systolic PAP 3 months after the treatment. The multivariable analysis<br />showed that none of the CMR findings was an independent predictor of a more systolic PAP<br />decline.<br />Conclusions: Although we found no significant relationship between CMR findings and systolic<br />PAP changes after MS treatment, the result of this study can be used for further<br />investigations in this regard. https://journal.iha.org.ir/article_82756_8eca019dc15a07d4347cd88b8893e5ee.pdf