Iranian Heart Association Iranian Heart Journal 19 2 2018 06 01 Prevalence and Prognostic Significance of Pericardial Effusion in Native Valve Endocarditis Based on Data From the Iranian Registry of Infective Endocarditis (IRIE) 36 43 82812 EN Ata Firouzi Cardiovascular Intervention Research Center, Rajaie Cardiovascular, Medical, and Research Center; Iran University of Medical Sciences, Tehran, IR Iran Ronak Ahmadi Rajaie Cardiovascular, Medical, and Research Center; Iran University of Medical Sciences, Tehran, IR Iran Nargeuss Abbaszade Marzbali Rajaie Cardiovascular, Medical, and Research Center; Iran University of Medical Sciences, Tehran, IR Iran Anita Sadeghpour Echocardiography Research Center, Rajaie Cardiovascular, Medical, and Research Center, Iran University of Medical Sciences, Tehran, IR Iran Zeinab Norouzi Cardiovascular Intervention Research Center, Rajaie Cardiovascular, Medical, and Research Center; Iran University of Medical Sciences, Tehran, IR Iran Hamidreza Pasha Rajaie Cardiovascular, Medical, and Research Center; Iran University of Medical Sciences, Tehran, IR Iran Reza Golpira Rajaie Cardiovascular, Medical, and Research Center; Iran University of Medical Sciences, Tehran, IR Iran Yousef Moghaddam Rajaie Cardiovascular, Medical, and Research Center; Iran University of Medical Sciences, Tehran, IR Iran Nasim Naderi Rajaie Cardiovascular, Medical, and Research Center; Iran University of Medical Sciences, Tehran, IR Iran Journal Article 2019 02 17 Background: The presence of pericardial effusion (PE) in the setting of infective endocarditis (IE) may<br />be a sign of more severe IE. In this study, we aimed to determine the prevalence and prognostic<br />significance of PE in patients with native valve IE.<br />Methods: The Iranian Registry of Infective Endocarditis (IRIE) is a single-center observational<br />hospital-based study of patients with IE. Between 2002 and 2015, all patients with a diagnosis<br />of IE who had been enrolled in the IRIE were evaluated.<br />Results: A total of 445 patients (68.3% male) were enrolled in this registry, and 221 (49.7%) patients<br />had PE. PE was more prevalent in the patients with native valve IE and those with right-heart<br />involvement (65% in right-heart IE vs 50% in left-heart IE; P=0.002). The rate of in-hospital<br />mortality was 20% and 19.2% in the patients with and without PE, respectively, and the<br />presence of PE was not a predictor of in-hospital death in our multivariate analyses.<br />Additionally, there was no relationship between the rates of IE-related complications and the<br />severity of PE. However, the prevalence of PE was higher in the patients with right-sided IE as<br />well as in those with aortic root abscess and systemic emboli at presentation.<br />Conclusions: The prevalence of PE in the setting of IE was relatively high in the present study. Most<br />cases of PE had mild effusion, and there was no relationship between the severity of PE and IErelated complications as well as in-hospital mortality. https://journal.iha.org.ir/article_82812_6461f013ca905cc0d8036b1fbb25b2fe.pdf