SURGICAL PATHOLOGY LABORATORY, SHAHEED RAJAIE CARDIOVASCULAR, MEDICAL AND RESEARCH CENTER, MELLAT PARK, VALI ASR AVE., TEHRAN, IRAN
Abstract
We present a 56-year-old woman who came to the emergency department with an exertional dyspnea of recent onset. A transthoracic echocardiographic examination revealed two round masses in her left atrium with mild mitral stenosis and mild-to-moderate mitral valve regurgitation. Her laboratory data were unremarkable except for a mild anemia. Surgical excision of the masses was performed, and two creamy-white fleshy tumors were removed. On cross section, they were solid and creamy-brown with gritty areas. Histopathological examination showed extensive sheets of round to oval cells, and hemangiopericytoma-like patterns. Also, multiple lobules of well-differentiated hyaline cartilage were present. An immunohistochemistry (IHC) panel revealed that the chondroid areas were reactive for S100 protein. The round cells expressed CD99 with focal positivity for NSE (neuron-specific enolase), but were negative for the following cytokeratin, CD34, factor VIII, actin, and desmin. Therefore, the cells were mesenchymal in origin with chondroid differentiation, and the final diagnosis was a mesenchymal chondrosarcoma. A full-scale investigation into the source of the tumor was unrevealing. Shortly after her discharge from the hospital, she developed an embolic cerebrovascular accident.
MOZAFFARI, K., YAZDANI BIUCKI, F., OMRANI, G., HASHEMI, J., & AMINI, A. (2010). EXERTIONAL DYSPNEA AND LEFT ATRIAL MASS. Iranian Heart Journal, 11(3), 47-49.
MLA
KAMBIZ MOZAFFARI; FARZAD, YAZDANI BIUCKI; GHOLAMREZA OMRANI; JAFAR HASHEMI; AHMAD AMINI. "EXERTIONAL DYSPNEA AND LEFT ATRIAL MASS". Iranian Heart Journal, 11, 3, 2010, 47-49.
HARVARD
MOZAFFARI, K., YAZDANI BIUCKI, F., OMRANI, G., HASHEMI, J., AMINI, A. (2010). 'EXERTIONAL DYSPNEA AND LEFT ATRIAL MASS', Iranian Heart Journal, 11(3), pp. 47-49.
VANCOUVER
MOZAFFARI, K., YAZDANI BIUCKI, F., OMRANI, G., HASHEMI, J., AMINI, A. EXERTIONAL DYSPNEA AND LEFT ATRIAL MASS. Iranian Heart Journal, 2010; 11(3): 47-49.