1
Department of Internal Medicine, Hue University of Medicine and Pharmacy, Hue University, Hue, Vietnam.
2
Department of Cardiology, Cardiovascular Center, Hue Central Hospital, Hue, Vietnam.
Abstract
Background: ST-elevation myocardial infarction (STEMI) is an acute cardiovascular condition associated with a high mortality rate. Primary percutaneous coronary intervention (pPCI) is the recommended treatment for STEMI. Nonetheless, complications may arise during and after the procedure. The present study evaluated the relationship between the neutrophil-to-lymphocyte ratio (NLR) and major adverse cardiac events occurring within 12 months following pPCI.
Methods: The current retrospective cohort study involved 148 STEMI patients who met the inclusion criteria and underwent pPCI at the Cardiovascular Center of Hue University of Medicine and Pharmacy Hospital. The patients were monitored for 12 months post-intervention.
Results: The rates of cardiovascular mortality, nonfatal MI, nonfatal cerebrovascular stroke, and in-stent restenosis increased as NLR rose. Logistic regression analysis indicated that NLR was an independent predictive factor (OR, 2.015, 95% CI, 1.718 to 2.984; P = 0.007).
Conclusions: NLR is an independent predictor of cardiovascular complications in patients with STEMI following pPCI. This straightforward, cost-effective, and highly accurate tool can be readily implemented in medical centers, enabling physicians to assess risks and develop appropriate preventive strategies for patients with STEMI after pPCI. (Iranian Heart Journal 2025; 26(3): 15-26)
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Hoang Anh,T , Doan Pham Phuoc,L and Tran Tu,N . (2025). Neutrophil-to-Lymphocyte Ratio and Major Adverse Cardiac Events in Patients With ST-Elevation Myocardial Infarction Undergoing Primary PCI in Vietnam. Iranian Heart Journal, 26(3), 15-26.
MLA
Hoang Anh,T , , Doan Pham Phuoc,L , and Tran Tu,N . "Neutrophil-to-Lymphocyte Ratio and Major Adverse Cardiac Events in Patients With ST-Elevation Myocardial Infarction Undergoing Primary PCI in Vietnam", Iranian Heart Journal, 26, 3, 2025, 15-26.
HARVARD
Hoang Anh T, Doan Pham Phuoc L, Tran Tu N. (2025). 'Neutrophil-to-Lymphocyte Ratio and Major Adverse Cardiac Events in Patients With ST-Elevation Myocardial Infarction Undergoing Primary PCI in Vietnam', Iranian Heart Journal, 26(3), pp. 15-26.
CHICAGO
T Hoang Anh, L Doan Pham Phuoc and N Tran Tu, "Neutrophil-to-Lymphocyte Ratio and Major Adverse Cardiac Events in Patients With ST-Elevation Myocardial Infarction Undergoing Primary PCI in Vietnam," Iranian Heart Journal, 26 3 (2025): 15-26,
VANCOUVER
Hoang Anh T, Doan Pham Phuoc L, Tran Tu N. Neutrophil-to-Lymphocyte Ratio and Major Adverse Cardiac Events in Patients With ST-Elevation Myocardial Infarction Undergoing Primary PCI in Vietnam. Iranian Heart Journal. 2025;26(3):15-26.
